He is famous in the annals of forensic science for developing the species precipitin test, known as the Uhlenhuth test, which could distinguish human blood from animal blood in 1901, a discovery which had tremendous importance in criminal justice in the 20th century.
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Further, " C . immitis " was identified as the culprit of respiratory disorders previously called San Joaquin Valley fever, desert fever, and Valley fever, and a serum precipitin test was developed by Charles E . Smith that was able to detect an acute form of the infection.
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